MYOCARDIAL-ISCHEMIA RELATED TO ERGOT ALKALOIDS - A CASE-REPORT AND LITERATURE-REVIEW

被引：32

作者：

GALER, BS

LIPTON, RB

SOLOMON, S

NEWMAN, LC

SPIERINGS, ELH

机构：

[1] BRIGHAM & WOMENS HOSP,DIV NEUROL,HEADACHE SECT,BOSTON,MA 02115

[2] YESHIVA UNIV ALBERT EINSTEIN COLL MED,DEPT NEUROL,BRONX,NY 10461

[3] YESHIVA UNIV ALBERT EINSTEIN COLL MED,DEPT PSYCHIAT,BRONX,NY 10461

[4] MONTEFIORE MED CTR,HEADACHE UNIT,BRONX,NY 10467

来源：

HEADACHE | 1991年 / 31卷 / 07期

关键词：

ERGOTAMINE; METHYSERGIDE; VASOCONSTRICTION; CORONARY;

D O I：

10.1111/j.1526-4610.1991.hed3107446.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Ergotamine tartrate and methysergide are widely used headache treatments with important vasoconstrictive properties. We report a 31-year-old man with cluster headaches who developed severe, prolonged myocardial ischemia following combination therapy with ergotamine tartrate and methysergide. We reviewed the cardiovascular complications of each agent alone and in combination. Given the pharmacologic similarity of these agents, we propose that they may have additive or synergistic cardiac toxicity, at least in vulnerable individuals. We recommend caution when these agents are used together.

引用

页码：446 / 450

页数：5

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AMELI FM, 1977, CAN J SURG, V20, P158

[2]

APOSES J, 1979, ARCH SURG-CHICAGO, V114, P964

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