SYSTEMATIC STUDY OF THE PHARMACOLOGICAL ACTIVITIES OF DOPAMINE ANTAGONISTS

被引：219

作者：

NIEMEGEERS, CJE

JANSSEN, PAJ

机构：

[1] Janssen Pharmaceutica Research Laboratories

来源：

LIFE SCIENCES | 1979年 / 24卷 / 24期

关键词：

D O I：

10.1016/0024-3205(79)90096-1

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The so-called dopamine (DA)-antagonists possess a wide variety of pharmacological activities. The present paper analyses some comparative data that were obtained in the Janssen Research Laboratories, using a large series of DA-antagonists in a representative set of pharmacological tests. This study illustrates the relative importance of the different pharmacological properties of these compounds, provides a tool for further meaningful pharmacological and biochemical research in this area, and discusses the therapeutic potential of these drugs. © 1979.

引用

页码：2201 / 2216

页数：16

共 46 条

[1] SLEEP DISORDERS IN PATIENTS WITH SEVERE MENTAL DEPRESSION - DOUBLE-BLIND PLACEBO-CONTROLLED EVALUATION OF VALUE OF PIPAMPERONE (DIPIPERON) [J].