ADENYLATE-CYCLASE AND ATPASE ACTIVITIES IN RED-CELL MEMBRANES OF PATIENTS AND GENETIC CARRIERS OF DUCHENNE MUSCULAR-DYSTROPHY

被引:9
作者
WACHOLTZ, MC [1 ]
RAIBLE, DG [1 ]
JACKOWSKI, S [1 ]
RODAN, SB [1 ]
RODAN, GA [1 ]
SHAAFI, RI [1 ]
机构
[1] UNIV CONNECTICUT,CTR HLTH SCI,DEPT ORAL BIOL,FARMINGTON,CT 06032
关键词
D O I
10.1016/0009-8981(79)90436-4
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
Basal adenylate cyclase activity was increased in red cell ghosts from both patients with Duchenne muscular dystrophy and their mothers when the activities were compared to proper age-matched controls. The activity of ATPase measured in the presence of Na+, K+, and Mg2+ was not found to be different in erythrocyte ghosts from Duchenne dystrophic patients, age-matched controls, or the mothers of Duchenne patients, and ouabain inhibited ATPase in ghosts to the same extent in all membrane preparations. © 1979.
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页码:255 / 259
页数:5
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