PURIFICATION AND PARTIAL CHARACTERIZATION OF AN ANTIBIOTIC PRODUCED BY MYXOCOCCUS-CORALLOIDES

被引：10

作者：

ARIAS, JM

RODRIGUEZ, C

MONTOYA, E

机构：

[1] Department of Microbiology, Faculty of Sciences, University of Granada, Granada, Spain

来源：

JOURNAL OF ANTIBIOTICS | 1979年 / 32卷 / 03期

关键词：

D O I：

10.7164/antibiotics.32.205

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

A strain of Myxococcus coralloides producing an antibiotic capable of inhibiting growth of Gram-positive bacteria was isolated. Antibiotic production occurred during vegetative growth but not during myxospore formation. The antibiotic was extracted from the growth medium with chloroform and purified by adsorption on silicic acid and by preparative silica gel thin-layer chromatography. The purified antibiotic showed a resistance to heat, acid, alkali and proteolytic enzymes. Chromatographic and electrophoretic behavior as well as infrared, ultraviolet and mass spectra are presented. © 1979, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.

引用

页码：205 / 211

页数：7

共 22 条

[1]

ARIAS JM, 1976, LABORATORIO, V370, P317

[2]

Balassa G, 1971, Curr Top Microbiol Immunol, V56, P99

[3] DEOXYRIBONUCLEIC ACID DEGRADATION AND LETHAL EFFECT BY MYXIN IN ESCHERICHIA-COLI [J].