EFFECT OF LSD-25 ON MITOTIC AND MEIOTIC CHROMOSOMES OF MICE AND MONKEYS

被引：17

作者：

EGOZCUE, J

IRWIN, S

机构：

[1] Instituto de Investigaciones Citológicas de la Caja de Ahorros y M.P. de Valencia, Valencia

[2] Department of Psychopharmacology, Oregon Regional Primate Research Center, Beaverton

[3] Department of Psychiatry, University of Oregon Medical School, Portland

来源：

HUMANGENETIK | 1969年 / 8卷 / 02期

关键词：

D O I：

10.1007/BF00295831

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Chromosomal studies were carried out in bone marrow and testes of mice treated with lysergic acid diethylamide (LSD-25) in acute and chronic experiments, in blood cultures of rhesus monkeys (Macaca mulatta) treated with LSD-25 in vitro, and in blood cultures and testicular preparations of rhesus macaques treated with LSD. No increase in chromosomal damage was observed in bone marrow or testes, but all blood cultures treated with LSD in vitro and some of the blood cultures from rhesus macaques treated in vitro showed a significant increase in chromosomal breaks and rearrangements. © 1969 Springer-Verlag.

引用

页码：86 / &

共 28 条

[1] LYSERGIC ACID DIETHYLAMIDE (LSD-25) AND CHROMOSOME BREAKS [J].