MANGANESE LEVELS IN A JAUNDICED LONG-TERM TOTAL PARENTERAL-NUTRITION PATIENT - POTENTIATION OF HALOPERIDOL TOXICITY - CASE-REPORT AND LITERATURE-REVIEW

被引:36
作者
MEHTA, R
REILLY, JJ
机构
[1] Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
关键词
D O I
10.1177/0148607190014004428
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Manganese is vital in human nutrition. When oral intake is precluded, the recommended parenteral supplementation is 0.15 to 0.8 mg/day. Manganese is excreted primarily in the bile; during cholestasis, serum manganese levels may rise, and manganese toxicity ensue. Neuropsychiatric symptoms are prominent. Phenothiazine-derivative drugs may potentiate manganese toxicity. Serum or whole blood manganese levels should guide manganese therapy in jaundiced patients. (Journal of Parenteral and Enteral Nutrition 14 :428-430, 1990). © 1990, American Society for Parenteral and Enteral Nutrition. All rights reserved.
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页码:428 / 436
页数:9
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