SOMATIC-CELL MAPPING OF BOVINE EC-SOD AND SOD1L-LOCI

被引：7

作者：

GALLAGHER, DS ^{[1
]}

GIBBS, LS ^{[1
]}

SHAFFER, JB ^{[1
]}

WOMACK, JE ^{[1
]}

机构：

[1] NEW YORK STATE DEPT HLTH,BIOCHEM & GENET TOXICOL LAB,ALBANY,NY 12201

来源：

GENOMICS | 1992年 / 12卷 / 03期

关键词：

D O I：

10.1016/0888-7543(92)90457-4

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

cDNA probes of human extracellular superoxide dismutase (EC-SOD) and bovine superoxide dismutase 1 (SOD1) genes were hybridized to Southern blots containing genomic DNAs from cow-rodent somatic cell lines segregating bovine chromosomes. The SOD1 probe identified two loci: the coding locus (SOD1)), which mapped to U11. EC-SOD mapped to bovine U15. The mapping of EC-SOD to human chromosome 4, and our mapping of EC-SOD to U15, further defines a region of extensive syntenic conservation between humans and domestic cows. © 1992.

引用

页码：610 / 612

页数：3

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