METALLOBIOCHEMISTRY OF RNA - CO(NH3)6(3+) AS A PROBE FOR MG2+(AQ) BINDING-SITES

被引：75

作者：

COWAN, JA

机构：

[1] Evans Laboratory of Chemistry, The Ohio State University, Columbus, OH

来源：

JOURNAL OF INORGANIC BIOCHEMISTRY | 1993年 / 49卷 / 03期

关键词：

D O I：

10.1016/0162-0134(93)80002-Q

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Co(NH3)63+ may serve as a probe of outer sphere complexation by Mg(H2O)62+ with RNA. The number of metal binding sites may be quantitatively assessed by optical spectroscopy (55-130, depending on background [K+]). Novel coordination-induced features have been observed in circular dichroism spectra.

引用

页码：171 / 175

页数：5

共 23 条

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