SHEAR-STRESS AT A COMPLIANT MODEL OF THE HUMAN CAROTID BIFURCATION

被引:63
作者
ANAYIOTOS, AS
JONES, SA
GIDDENS, DP
GLAGOV, S
ZARINS, CK
机构
[1] JOHNS HOPKINS UNIV,SCH ENGN,BALTIMORE,MD 21218
[2] UNIV CHICAGO,SCH MED,DEPT PATHOL SURG,CHICAGO,IL 60637
来源
JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME | 1994年 / 116卷 / 01期
关键词
D O I
10.1115/1.2895710
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
To investigate the role of a compliant wall to the near wall hemodynamic flowfield, two models of the carotid bifurcation were constructed. Both were of identical infernal geometries, however, one was made of compliant material which produced approximately the same degree of wall motion as that occurring in vivo while the other one was rigid. The inner geometries were formed from the same mold so that the configurations are directly comparable. Each model was placed in a pulsatile flow system that produced a physiologic flow waveform. Velocity was measured with a single component Laser system and wall shear rate was estimated from near wall data. Wall motion in the compliant model was measured by a wall motion transducer and the maximum diameter change varied between 4-7 percent in the model with the greatest change at the axis intersection. The mean shear stress in the compliant model was observed to be smaller by about 30 percent at most locations. The variation in peak shear stress was greater and occasionally reached as much as 100 percent with the compliant model consistently having smaller positive and negative peaks. The separation point was seen to move further upstream in the compliant cast. The modified flowfield in the presence of a compliant wall can then be important in the hemodynamic theory of atherogenesis.
引用
收藏
页码:98 / 106
页数:9
相关论文
共 30 条
[1]  
ANAYIOTOS A, 1990, THESIS GEORGIA I TEC
[2]   DIAMETER OF INTACT CAROTID ARTERY IN MAN AND ITS CHANGE WITH PULSE PRESSURE [J].
ARNDT, JO ;
KLAUSKE, J ;
MERSCH, F .
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 1968, 301 (03) :230-&
[3]  
BALASUBRAMNIAN K, 1980, THESIS GEORGIA I TEC
[4]   ATHEROMA AND ARTERIAL WALL SHEAR - OBSERVATION, CORRELATION AND PROPOSAL OF A SHEAR DEPENDENT MASS TRANSFER MECHANISM FOR ALTHEROGENESIS [J].
CARO, CG ;
FITZGERA.JM ;
SCHROTER, RC .
PROCEEDINGS OF THE ROYAL SOCIETY SERIES B-BIOLOGICAL SCIENCES, 1971, 177 (1046) :109-+
[5]   MEASUREMENT OF WALL MOTION AND WALL SHEAR IN A COMPLIANT ARTERIAL CAST [J].
DETERS, OJ ;
BARGERON, CB ;
MARK, FF ;
FRIEDMAN, MH .
JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 1986, 108 (04) :355-358
[6]  
DUNCAN DD, 1990, ASME MAY, P183
[7]  
DUTTA A, 1989, BIORHEOLOGY, V26, P1
[8]   DISTRIBUTION OF FATTY AND FIBROUS PLAQUES IN YOUNG HUMAN CORONARY-ARTERIES [J].
FOX, B ;
JAMES, K ;
MORGAN, B ;
SEED, A .
ATHEROSCLEROSIS, 1982, 41 (2-3) :337-347
[9]   CORRELATION BETWEEN INTIMAL THICKNESS AND FLUID SHEAR IN HUMAN ARTERIES [J].
FRIEDMAN, MH ;
HUTCHINS, GM ;
BARGERON, CB ;
DETERS, OJ ;
MARK, FF .
ATHEROSCLEROSIS, 1981, 39 (03) :425-436
[10]  
FRY DL, 1972, ATHEROSCLEROSIS CORO, P85