LEUKOTACTIC FACTOR PRODUCED BY SENSITIZED LYMPHOCYTES

被引：253

作者：

WARD, PA

REMOLD, HG

DAVID, JR

机构：

[1] Armed Forces Institute of Pathology, Washington

[2] Robert B. Brigham Hospital, Harvard Medical School, Boston

来源：

SCIENCE | 1969年 / 163卷 / 3871期

关键词：

D O I：

10.1126/science.163.3871.1079

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Lymph node lymphocytes obtained from guinea pigs exhibiting delayed hypersensitivity are stimulated in vitro by specific antigen to produce a soluble factor that is chemotactic in vitro for mononuclear macrophages. The material is nondialyzable, relatively heat stable, and elutes from Sephadex G-100 in the fraction containing molecules smaller than immunoglobulins.

引用

页码：1079 / &

共 23 条

[1] REACTIONS IN VIVO AND IN VITRO PRODUCED BY A SOLUBLE SUBSTANCE ASSOCIATED WITH DELAYED-TYPE HYPERSENSITIVITY [J].