FIRST REGIOSELECTIVE MUCOR-MIEHEI LIPASE-CATALYZED SYNTHESIS OF DIESTER CROWNS - NEW MACROCYCLES CONTAINING A 1,3-BIS(1H-PYRAZOL-1-YL)PROPANE UNIT

被引：8

作者：

FIERROS, M ^{[1
]}

RODRIGUEZFRANCO, MI ^{[1
]}

NAVARRO, P ^{[1
]}

CONDE, S ^{[1
]}

机构：

[1] CSIC,INST QUIM MED,E-28006 MADRID,SPAIN

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1994年 / 4卷 / 21期

关键词：

D O I：

10.1016/S0960-894X(01)80276-6

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Diester crowns 4a-c have been prepared for the first time by regioselective lipase-catalyzed transesterification. The synthesized new ester crowns include a 1,3-bis(1H-pyrazol-1-yl)propane unit as a part of the macrocycle. Acyclic intermediates 3a-c were also obtained.

引用

收藏

页码：2523 / 2526

页数：4

相关论文

共 18 条

[1] FORMATION OF MONO-NUCLEAR AND DI-NUCLEAR COMPLEXES OF ZN2+ FROM A 26 MEMBERED TETRAESTER CROWN OF 3,5-DISUBSTITUTED PYRAZOLE ABLE TO ACT AS NEUTRAL AND DIANIONIC LIGAND [J].

ACERETE, C ;

BUENO, JM ;

CAMPAYO, L ;

NAVARRO, P ;

RODRIQUEZFRANCO, MI ;

SAMAT, A .

TETRAHEDRON, 1994, 50 (16) :4765-4774

[2] SYNTHESIS OF NEW MACROCYCLIC POLYETHER DIESTER OR TETRAESTER LIGANDS CONTAINING PYRAZOLE UNITS [J].

ELGUERO, J ;

NAVARRO, P ;

FRANCO, MIR .

CHEMISTRY LETTERS, 1984, (03) :425-428

[3]

Elguero J., 1984, COMPR HETEROCYCL CHE, P167, DOI DOI 10.1016/B978-008096519-2.00072-2

[4]

[5]

FIERROS M, 1993, HETEROCYCLES, V36, P2019

[6] ENZYMATIC-SYNTHESIS OF MACROCYCLIC LACTONES [J].

GUO, ZW ;

SIH, CJ .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1988, 110 (06) :1999-2001

[7] SYNTHESIS, CYTOSTATIC AND TRICHOMONACIDE ACTIVITIES OF 3,5-BIS-(HALOMETHYL)PYRAZOLES [J].

ITURRINO, L ;

NAVARRO, P ;

RODRIGUEZFRANCO, MI ;

CONTRERAS, M ;

ESCARIO, JA ;

MARTINEZ, A ;

PARDO, MD .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 1987, 22 (05) :445-451

[8] THERMODYNAMIC AND KINETIC DATA FOR CATION MACROCYCLE INTERACTION [J].

IZATT, RM ;

BRADSHAW, JS ;

NIELSEN, SA ;

LAMB, JD ;

CHRISTENSEN, JJ .

CHEMICAL REVIEWS, 1985, 85 (04) :271-339

[9] SUPRAMOLECULAR CHEMISTRY - SCOPE AND PERSPECTIVES MOLECULES, SUPERMOLECULES, AND MOLECULAR DEVICES [J].

LEHN, JM .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1988, 27 (01) :89-112

[10] [18]-N303 AZA-OXA MACROCYCLE - SELECTIVE RECEPTOR UNIT FOR PRIMARY AMMONIUM CATIONS [J].

LEHN, JM ;

VIERLING, P .

TETRAHEDRON LETTERS, 1980, 21 (14) :1323-1326