EVIDENCE FOR AN ELECTROGENIC SODIUM PUMP IN SMOOTH MUSCLE

被引:42
作者
TAYLOR, GS
PATON, DM
DANIEL, EE
机构
[1] Department of Pharmacology, University of Alberta, Edmonton 7, Alta.
来源
LIFE SCIENCES PART 1 PHYSIOLOGY AND PHARMACOLOGY AND PART 2 BIOCHEMISTRY GENERAL AND MOLECULAR BIOLOGY | 1969年 / 8卷 / 13P1期
关键词
D O I
10.1016/0024-3205(69)90268-9
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Sodium enriched pregnant rat myometrial cell hyperpolarized within two minutes of exposure to potassium containing medium without detectable change in tissue potassium content. The hyperpolarization, which exceeded the potassium equilibrium potential, was temperature- and potassium-dependent and abolished by ouabain. These findings suggest that an electrogenic sodium pump is responsible for the observed hyperpolarization. © 1969.
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页码:769 / &
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