ASSIGNMENT OF STRUCTURAL BETA-GALACTOSIDASE LOCI TO HUMAN CHROMOSOME-3 AND CHROMOSOME-22

被引：6

作者：

DEWIT, J

HOEKSEMA, HL

BOOTSMA, D

WESTERVELD, A

机构：

[1] Department of Cell Biology and Genetics, Erasmus University, Rotterdam

来源：

HUMAN GENETICS | 1979年 / 51卷 / 03期

关键词：

D O I：

10.1007/BF00283392

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Hybrid cell lines isolated after fusions between Chinese hamster E36 cells and normal human white blood cells were analyzed for human β-galactosidase isoenzymes and for human chromosomes, especially 3, 12, and 22, the candidates for bearing a β-galactosidase locus. Results of neuraminidase treatment of the cell lysates and immunological studies showed that in man two structural β-galactosidase loci are present and can be assigned to chromosomes 3 and 22. No correlation was found between the expression of human β-galactosidase and the presence of human chromosome 12. © 1979 Springer-Verlag.

引用

页码：259 / 267

页数：9

共 23 条

[1] BOOTSMA D, 1977, 4TH INT WORKSH HUM G
[2] BRUNS GAP, 1977, 4TH INT WORKSH HUM G
[3] FERGUSONSMITH MA, 1977, 4TH INT WORKSH HUM G
[4] GENETIC-HETEROGENEITY IN GM1-GANGLIOSIDOSIS
GALJAARD, H
HOOGEVEEN, A
KEIJZER, W
DEWITVERBEEK, HA
REUSER, AJJ
HO, MW
ROBINSON, D
[J]. NATURE, 1975, 257 (5521) : 60 - 62
[5] GILLIN FD, 1972, GENETICS, V72, P239
[6] AN IMPROVED NUTRIENT SOLUTION FOR DIPLOID CHINESE HAMSTER AND HUMAN CELL LINES
HAM, RG
[J]. EXPERIMENTAL CELL RESEARCH, 1963, 29 (03) : 515 - &
[7] HOEKSEMA HL, BIOCH BIOPHYS ACTA
[8] LOCALIZATION OF GENES ON HUMAN CHROMOSOMES BY STUDIES OF HUMAN-CHINESE HAMSTER SOMATIC-CELL HYBRIDS - ASSIGNMENT OF PGM3 TO CHROMOSOME-C6 AND REGIONAL MAPPING OF PGD, PGM1 AND PEP-C GENES ON CHROMOSOME-A1
JONGSMA, A
VANSOMER.H
WESTERVELD, A
HAGEMEIJER, A
PEARSON, P
[J]. HUMANGENETIK, 1973, 20 (03): : 195 - 202
[9] SELECTION OF HYBRIDS FROM MATINGS OF FIBROBLASTS IN VITRO + THEIR PRESUMED RECOMBINANTS
LITTLEFIELD, JW
[J]. SCIENCE, 1964, 145 (363) : 709 - &
[10] Meera Khan P, 1971, Arch Biochem Biophys, V145, P470

← 1 2 3 →