THE SCREENING FOR COMMON-DRUGS OF ABUSE IN WHOLE-BLOOD BY MEANS OF EMIT-ETS AND FPIA-ADX URINE IMMUNOASSAYS

被引：5

作者：

MAIER, RD ^{[1
]}

ERKENS, M ^{[1
]}

HOENEN, H ^{[1
]}

BOGUSZ, M ^{[1
]}

机构：

[1] RHEIN WESTFAL TH AACHEN,INST FORENS MED,W-5100 AACHEN,GERMANY

来源：

INTERNATIONAL JOURNAL OF LEGAL MEDICINE | 1992年 / 105卷 / 02期

关键词：

DRUGS OF ABUSE; ENZYME MULTIPLIED IMMUNOASSAY (EMIT); FLUORESCENCE POLARIZATION IMMUNOASSAY (FPIA); ACETONE PRECIPITATION; ULTRAFILTRATION;

D O I：

10.1007/BF02340835

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

The purpose of the paper was to compare the performance of ETS (EMIT) and ADx (FPIA) analyzers for screening blood samples for drugs of abuse after 2 alternative pretreatment procedures (acetone precipitation and ultrafiltration). Cannabinoids, benzodiazepines and benzoylecgonine were not detectable with both assays after ultrafiltration. The detectability of morphine in blood ultrafiltrates was distinctly lower than after acetone precipitation. The comparison of results obtained with ETS and ADx after acetone precipitation showed that ETS assay is slightly more sensitive but ADx is slightly more reproducible. Both assays may be used for blood examination with similar cut-off values. The ETS analyzer gave much better analytical performance (speed, flexibility) and lower reagent costs than the ADx analyzer.

引用

页码：115 / 119

页数：5

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