AUTORADIOGRAPHIC DETECTION OF TRIIODOTHYRONINE IN NUCLEI FROM NORMAL AND HYPOTHYROID RAT-LIVER

被引：16

作者：

TORRESANI, J

GHARBI, J

LISSITZKY, S

MIRRE, C

DELGROSSI, MH

STAHL, A

机构：

[1] FAC MED MARSEILLE,HISTOL EMBRYOL LAB 2,F-13385 MARSEILLE 4,FRANCE

[2] FAC MED MARSEILLE,INSERM,U38,F-13385 MARSEILLE 4,FRANCE

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1979年 / 86卷 / 02期

关键词：

D O I：

10.1016/0006-291X(79)90875-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Nuclear triiodothyronine was visualized by light and electron microscope autoradiography of liver nuclei isolated after intraperitoneal injection of [125I] triiodothyronine in rats. The nuclear hormone, essentially bound to the putative nuclear triiodothyronine receptor, was found mostly associated with the border of condensed chromatin. © 1979.

引用

收藏

页码：371 / 378

页数：8

相关论文

共 27 条

[1] ELECTRON-MICROSCOPIC AUTORADIOGRAPHY OF I-125-TRIIODOTHYRONINE IN RAT POSTERIOR PITUITARY AND MEDIAN-EMINENCE [J].

BARSELLA, P ;

STEIN, O ;

GROSS, J .

ENDOCRINOLOGY, 1973, 93 (06) :1410-1422

[2] THYROID-HORMONE RECEPTORS FROM LIVER NUCLEI - CHARACTERISTICS OF RECEPTOR FROM NORMAL, THYROIDECTOMIZED, AND TRIIODOTHYRONINE-TREATED RATS - MEASUREMENT OF OCCUPIED AND UNOCCUPIED RECEPTORS, AND CHROMATIN BINDING OF RECEPTORS [J].

BERNAL, J ;

COLEONI, AH ;

DEGROOT, LJ .

ENDOCRINOLOGY, 1978, 103 (02) :403-413

[3] BINDING OF T3 IN RAT-LIVER NUCLEI [J].

DEGROOT, LJ ;

STRAUSSER, JL .

ENDOCRINOLOGY, 1974, 95 (01) :74-83

[4] FACTORS INFLUENCING TRIIODOTHYRONINE BINDING PROPERTIES OF LIVER NUCLEAR RECEPTORS [J].

DEGROOT, LJ ;

TORRESANI, J ;

CARRAYON, P ;

TIRARD, A .

ACTA ENDOCRINOLOGICA, 1976, 83 (02) :293-304

[5] LOCALIZATION AND CHARACTERIZATION OF NEWLY SYNTHESIZED NUCLEAR-RNA IN ISOLATED RAT HEPATOCYTES [J].

FAKAN, S ;

PUVION, E ;

SPOHR, G .

EXPERIMENTAL CELL RESEARCH, 1976, 99 (01) :155-164

[6] SENSITIVITY IN ELECTRON-MICROSCOPE AUTORADIOGRAPHY FOR I-125 [J].

FERTUCK, HC ;

SALPETER, MM .

JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 1974, 22 (02) :80-87

[7] NUCLEAR THYROID-HORMONE RECEPTORS - EVIDENCE FOR ASSOCIATION WITH NUCLEOLAR CHROMATIN [J].

GARDNER, RS .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1975, 67 (02) :625-633

[8] EFFECT OF THYROID-HORMONES ON LEVEL OF HEPATIC MESSENGER-RNA FOR ALPHA2U GLOBULIN [J].

KURTZ, DT ;

SIPPEL, AE ;

FEIGELSON, P .

BIOCHEMISTRY, 1976, 15 (05) :1031-1036

[9]

LATHAM KR, 1976, J BIOL CHEM, V251, P7388

[10] A COMPARISON OF THE CONTENT OF DESOXYRIBOSENUCLEIC ACID (DNA) IN ISOLATED ANIMAL NUCLEI BY CYTOCHEMICAL AND CHEMICAL METHODS [J].

LEUCHTENBERGER, C ;

VENDRELY, R ;

VENDRELY, C .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1951, 37 (01) :33-38