CREVICULAR IGG ANTIBODIES AND RECOVERY OF LOCALLY IMPLANTED STREPTOCOCCUS-MUTANSR IN HUMANS

被引：4

作者：

CAMLING, E

GAHNBERG, L

KRASSE, B

机构：

[1] Department of Cariology, Faculty of Odontology, University of Göteborg, Uppsala, Göteborg

[2] Public Dental Health, Uppsala

来源：

ORAL MICROBIOLOGY AND IMMUNOLOGY | 1991年 / 6卷 / 03期

关键词：

STREPTOCOCCUS-MUTANS; ORAL IMPLANTATION; GINGIVAL CREVICULAR FLUID; PLAQUE BACTERIA; DENTAL CARIES;

D O I：

10.1111/j.1399-302X.1991.tb00467.x

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

This study was undertaken with the aim of examining the effect of highly different IgG antibody activities in gingival crevicular fluid (GCF) on the elimination of a streptomycin-resistant strain of Streptococcus mutans (S. mutans(R)) topically implanted on the tooth. Two groups of people were selected for the study, one with high and one with low specific IgG antibody activit (IgG antibody activity against S. mutans(R)) in GCF. During an experimental period of 15 d the specific IgG antibody activity in GCF in the same individual stayed on a relatively constant level. Between individuals, however, the specific IgG antibody activity varied considerably. The number of indigenous mutans streptococci and the number of implanted bacteria on the same tooth surface were strongly correlated. The implanted S. mutans(R) strain was rapidly eliminated in all subjects. No difference in the elimination of the implanted strain of S. mutans(R) could be demonstrated between the groups of high and low specific IgG antibody activity.

引用

页码：134 / 138

页数：5

共 38 条

[1]

Aaltonen AS, Tenovuo J, Lehtonen O-P, Increased dental caries activity in preschool children with low baseline levels of serum IgG antibodies against the bacterial species Streptococcus mutans, Arch Oral Biol, 32, pp. 55-60, (1987)

[2]

Bowen WH, A vaccine against dental caries A pilot experiment in monkeys (Macaca irus), Br Dent J, 126, pp. 159-160, (1969)

[3]

Bratthall D, Gahnberg L, Krasse B, Method for detecting IgA antibodies to Streptococcus mutans serotypes in parotid saliva, Arch Oral Biol, 23, pp. 843-849, (1978)

[4]

Camling E, Kohler B, Infection with the bacterium Streptococcus mutans and salivary IgA antibodies in mothers and their children, Arch Oral Biol, 32, pp. 817-823, (1987)

[5]

Camling E, Gahnberg L, Krasse B, The relationship between IgA antibodies to Streptococcus mutans antigens in human saliva and breastmilk and the number of indigenous oral Streptococcus mutans, Arch Oral Biol, 32, pp. 21-25, (1987)

[6]

Carlsson J, Nutritional requirements of Streptococcus sanguis, Arch Oral Biol, 17, pp. 1327-1332, (1972)

[7]

Challacombe SJ, Serum complement‐fixing antibodies in human dental caries, Caries Res, 8, pp. 84-95, (1974)

[8]

Challacombe SJ, Lehner T, Serum and salivary antibodies to cariogenic bacteria in man, Journal of Dental Research, 55, (1976)

[9]

Challacombe SJ, Russell MW, Hawkes J, Passage of intact IgG from plasma to the oral cavity via crevicular fluid, Clin Exp Immunol, 34, pp. 417-422, (1978)

[10]

Challacombe SJ, Russell MW, Hawkes JE, Bergmeier LA, Lehner T, Passage of immunoglobulins from plasma to the oral cavity in rhesus monkeys, Immunology, 35, pp. 923-931, (1978)

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