A NEW APPROACH TO THE SYNTHESIS OF ENANTIOMERICALLY PURE 2,3-DIAMINOACIDS THROUGH CHIRAL IMIDAZOLIDIN-2-ONES

被引：37

作者：

CARDILLO, G

ORENA, M

PENNA, M

SANDRI, S

TOMASINI, C

机构：

[1] Centro per lo Studio della Fisica delle Macromolecole - C.N.R. Dipartmento, Chimica G. Ciamician - Università di Bologna, 40126 Bologna, Via Selmi

来源：

TETRAHEDRON | 1991年 / 47卷 / 12-13期

关键词：

D O I：

10.1016/S0040-4020(01)96136-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of enantiomerically pure 5-iodomethylimidazolidin-2-ones (3a-c) and (4a-c) is reported, by means of iodocyclisation of allylic tosylureas (2a-c). Starting from pure (3a) and (4a), a synthesis of both (R)- and (S)-2,3-diaminopropanoic acid is described. Furthermore the cyclisation of the homoallylic tosylurea (2d), occurring with total diastereoselection, is depicted.

引用

页码：2263 / 2272

页数：10

共 21 条

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