REGIOSELECTIVE ACETYLATION OF SOME N-METHYLPYRROLE DERIVATIVES WITH ISOPROPENYL ACETATE AND DIFFERENT ACETIC ANHYDRIDES

We studied the reactions of some N-methylpyrrole derivatives with isopropenyl acetate and different acetic anhydrides. We have found that the reaction with isopropenyl acetate afforded 5-acetylpyrrole derivatives while with acetic anhydrides acetylation occurred on the alpha-carbon atom of the side-chain of pyrrole-2-acetic acid derivatives.