AN ONLINE METHOD FOR THE PREPARATION OF NCA [(CH3)-C-11]TRIFLUOROMETHANESULFONIC ACID METHYL-ESTER

被引：13

作者：

HOLSCHBACH, M

SCHULLER, M

机构：

[1] Institut für Nuklearchemie, Forschungszentrum Jülich GmbH

来源：

APPLIED RADIATION AND ISOTOPES | 1993年 / 44卷 / 05期

关键词：

D O I：

10.1016/0969-8043(93)90035-9

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

An improved on-line synthesis of the powerful methylation reagent, [(CH3)-C-11]methyl triflate, 1, is described. By means of a simple and cheap column technique this reagent is synthesized in an overall reaction time of 12 min in reproducible radiochemical yields of 90% (based on (CO2)-C-11), a radiochemical purity of 99% and a mean sp. act. of > 6000 Ci/mmol.

引用

页码：897 / 898

页数：2