AN ONLINE METHOD FOR THE PREPARATION OF NCA [(CH3)-C-11]TRIFLUOROMETHANESULFONIC ACID METHYL-ESTER

被引:13
作者
HOLSCHBACH, M
SCHULLER, M
机构
[1] Institut für Nuklearchemie, Forschungszentrum Jülich GmbH
关键词
D O I
10.1016/0969-8043(93)90035-9
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
An improved on-line synthesis of the powerful methylation reagent, [(CH3)-C-11]methyl triflate, 1, is described. By means of a simple and cheap column technique this reagent is synthesized in an overall reaction time of 12 min in reproducible radiochemical yields of 90% (based on (CO2)-C-11), a radiochemical purity of 99% and a mean sp. act. of > 6000 Ci/mmol.
引用
收藏
页码:897 / 898
页数:2
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