STUDY OF FLUORESCENT-ANTIBODIES DIRECTED AGAINST THE GUT EPITHELIUM OF SCHISTOSOMA-MANSONI .5. EGG GRANULOMA MODULATION BY AN IGM MONOCLONAL-ANTIBODY

被引：1

作者：

BOISSEAU, H ^{[1
]}

BENYOUNES, R ^{[1
]}

APPRIOU, M ^{[1
]}

TRIBOULEYDURET, J ^{[1
]}

TRIBOULEY, J ^{[1
]}

机构：

[1] UNIV BORDEAUX 2,FAC PHARM,IMMUNOL LAB,F-33076 BORDEAUX,FRANCE

来源：

ANNALES DE PARASITOLOGIE HUMAINE ET COMPAREE | 1993年 / 68卷 / 03期

关键词：

GRANULOMA; MONOCLONAL ANTIBODY; EGG; MIRACIDIUM; SCHISTOSOMA-MANSONI;

D O I：

10.1051/parasite/1993683115

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

The periovular granulomatous reaction has been reduced in vivo by an IgM monoclonal antibody. The granulomatous reaction has been obtained either in unsensitized, or sensitized as well as immunized mouse. The granulomatous reduction could be explained by a decrease in egg viability, owing to the fact that the monoclonal antibody is lethal against an in vitro miracidium suspension.

引用

页码：115 / 120

页数：6

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