GEOGRAPHIC ASSOCIATION OF HELICOBACTER-PYLORI ANTIBODY PREVALENCE AND GASTRIC-CANCER MORTALITY IN RURAL CHINA

被引：260

作者：

FORMAN, D

SITAS, F

NEWELL, DG

STACEY, AR

BOREHAM, J

PETO, R

CAMPBELL, TC

LI, J

CHEN, J

机构：

[1] PUBL HLTH LAB SERV, CTR APPL MICROBIOL & RES, DIV PATHOL, SALISBURY SP4 0JG, WILTS, ENGLAND

[2] PUBL HLTH LAB SERV, NUFFIELD DEPT CLIN MED, IMPERIAL CANC RES FUND, CANC STUDIES UNIT, SALISBURY SP4 0JG, WILTS, ENGLAND

[3] CORNELL UNIV, DIV NUTR SCI, ITHACA, NY 14853 USA

[4] CHINESE ACAD MED SCI, INST CANC, BEIJING, PEOPLES R CHINA

[5] CHINESE ACAD PREVENT MED, INST NUTR & FOOD HYG, BEIJING, PEOPLES R CHINA

来源：

INTERNATIONAL JOURNAL OF CANCER | 1990年 / 46卷 / 04期

关键词：

D O I：

10.1002/ijc.2910460410

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

To examine the geographic association between Helicobacter pylori infection and gastric cancer, we have assessed the prevalence of IgG antibodies to H. pylori in plasma samples taken in 1983 from 1882 men, aged 35‐64 years, in 46 rural counties of the People's Republic of China. The gastric cancer mortality rates in these counties in 1973‐75 varied from 3 per 1,000 (cumulative rate, 0‐64 years) to 69 per 1, 000. while the proportions of the population positive for H. pylori antibodies (based on an average of about 41 men per county) varied from 28% to 96%. After correction for the limited number of blood samples per county, the estimated correlation between H. pyori antibody prevalence and gastric cancer mortality was 40% (p = 0.02). No other type of cancer showed a significant association with H. pylori. Copyright © 1990 Wiley‐Liss, Inc., A Wiley Company

引用

页码：608 / 611

页数：4

共 22 条

[1] BORSCH GMA, 1989, EUR J GASTROEN HEPAT, V1, P27
[2] CORREA P, 1988, CANCER RES, V48, P3554
[3] CORREA P, 1989, CAMPYLOBACTER PYLORI, P139
[4] DEHESA M, 1989, Gastroenterology, V96, pA115
[5] DIXON MF, 1989, CAMPYLOBACTER PYLORI, P106
[6] THE CLINICAL-SIGNIFICANCE OF CAMPYLOBACTER-PYLORI
DOOLEY, CP
COHEN, H
[J]. ANNALS OF INTERNAL MEDICINE, 1988, 108 (01) : 70 - 79
[7] FOX JG, 1989, AM J GASTROENTEROL, V84, P775
[8] CAMPYLOBACTER-PYLORI AND PEPTIC-ULCER DISEASE
GRAHAM, DY
[J]. GASTROENTEROLOGY, 1989, 96 (02) : 615 - 625
[9] GUTIERREZ O, 1988, GASTROENTEROLOGY, V94, pA163
[10] HOWSON CP, 1986, EPIDEMIOL REV, V8, P1

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