STUDIES ON HEPATIC MICROSOMAL N-DEALKYLATION REACTION . MOLECULAR OXYGEN AS SOURCE OF OXYGEN ATOM

被引：61

作者：

MCMAHON, RE

CULP, HW

OCCOLOWITZ, JC

机构：

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1969年 / 91卷 / 12期

关键词：

D O I：

10.1021/ja01040a060

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：3389 / +

页数：1

共 10 条

[1]

BAKER JR, 1962, J BIOL CHEM, V237, P1309

[2]

Bell R. P., 1966, ADV PHYS ORG CHEM, P1, DOI DOI 10.1016/S0065-3160(08)60351-2

[3] METABOLIC INTERCONVERSIONS BETWEEN IMIPRAMINE ITS N-OXIDE AND ITS DESMETHYL DERIVATIVE IN RAT TISSUES IN VITRO [J].

BICKEL, MH ;

WEDER, HJ ;

AEBI, H .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1968, 33 (06) :1012-&

[4] TERTIARY AMINE OXIDE REARRANGEMENTS .1. MECHANISM [J].

CRAIG, JC ;

GLAZER, AN ;

DWYER, FP ;

HORNING, EC .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1961, 83 (08) :1871-&

[5] DETOXICATION MECHANISMS .3. SCOPE AND MECHANISM OF IRON-CATALYZED DEALKYLATION OF TERTIARY AMINE OXIDES [J].

FERRIS, JP ;

GERWE, RD ;

GAPSKI, GR .

JOURNAL OF ORGANIC CHEMISTRY, 1968, 33 (09) :3493-&

[6] TERT-AMINE OXIDE REARRANGEMENTS - N,N-DIMETHYLTRYPTAMINE OXIDE [J].

FISH, MS ;

JOHNSON, NM ;

HORNING, EC .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1956, 78 (15) :3668-3671

[7] DEMETHYLATION STUDIES .4. IN VITRO AND IN VIVO CLEAVAGE OF ALKYL- AND ARYLALKYL-P-NITROPHENYL ETHERS [J].

MCMAHON, RE ;

CULP, HW ;

MILLS, J ;

MARSHALL, FJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1963, 6 (04) :343-&

[8] THE OXIDATIVE DEMETHYLATION OF 1-PROPOXYPHENE AND 1-PROPOXYPHENE N-OXIDE BY RAT LIVER MICROSOMES [J].

MCMAHON, RE ;

SULLIVAN, HR .

LIFE SCIENCES, 1964, 3 (10) :1167-1174

[9] MICROSOMAL DEALKYLATION OF DRUGS - SUBSTRATE SPECIFICITY AND MECHANISM [J].

MCMAHON, RE .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1966, 55 (05) :457-&

[10] THE ROLE OF OXIDATION IN THE BIOGENESIS OF ALKALOIDS [J].

WENKERT, E .

EXPERIENTIA, 1954, 10 (08) :346-350

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