POSSIBLE ROLE OF LEUKOTRIENES IN GASTRITIS ASSOCIATED WITH CAMPYLOBACTER-PYLORI

被引：20

作者：

FUKUDA, T

KIMURA, S

ARAKAWA, T

KOBAYASHI, K

机构：

[1] Third Department of Internal Medicine, Osaka City university Medical School, Osaka

来源：

JOURNAL OF CLINICAL GASTROENTEROLOGY | 1990年 / 12卷

关键词：

Campylobacter pylori; Gastritis; Leukorienes;

D O I：

10.1097/00004836-199001001-00022

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

This study was done to evaluate the role of leukotrienes LTs) in gastritis associated with Campylobacter pylori. Biopsy specimens of gastric mucosa were obtained endocopically from 18 patients with nonulcer dyspepsia for lacteriological and histological examination and extraction of LTs. There was correlation between the LTB4 level in the nucosa and the degree of gastritis evaluated histologically. The level was higher when infiltration of neutrophils in the astric mucosa was more extensive. The LTB4 level in muosa infected with C. pylori was higher than that in noninected mucosa. These findings suggest that endogenous LTs nay be related to the pathogenesis of gastritis associated vith C. pylori. © 1990 Raven Press, Ltd., New York.

引用

页码：S131 / S134

页数：4

共 16 条

[1] ROLES OF ENDOGENOUS LEUKOTRIENES IN DAMAGE CAUSED BY ETHANOL IN ISOLATED RAT GASTRIC CELLS [J].