COMBINATION OF DEXAMETHASON AND DICLOFENAC DROPS FOR THE TREATMENT OF POST-CATARACT INFLAMMATION

In a prospective randomized double masked study including 40 patients we evaluated the anti-inflammatory effect of a combination of dexamethason acetate 0.1% + diclofenac 0.1% drops compared to dexamethasone acetate 0.1% + placebo drops, after ECCE + posterior chamber lens implantation. Anterior chamber (AC) flare and cells were measured with the laser flare-cell meter Kowa FC-1000. The group receiving the dexamethason-diclofenac combination showed a more rapid decrease of AC flare which was significant at days D3 (P < 0.003) and D12 (p < 0.028). The reduction of AC cells was comparable in both groups, showing however a strong tendency toward a lower cell count in the group receiving diclofenac at days D12 und D30 (p < 0.08). Tolerance of diclofenac was good and comparable to the placebo.