EVIDENCE FOR THE LONG-TERM BIOLOGICAL DISTRIBUTION OF TECHNEGAS PARTICLES

被引:11
作者
BURCH, WM
机构
[1] Department of Medicine and Clinical Science, J.C.S.M.R, Australian National University, Canberra, ACT, 2601
关键词
D O I
10.1097/00006231-199307000-00007
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Technegas is a suspension of structured graphite ellipsoids, between 5 and 20 nm in aerodynamic diameter and labelled, in a carrier gas of argon, with Tc-99m. Its emergence and rapidly expanding dinical usage (105 000 studies, 22 countries), as a unique dry insoluble microaerosol for diagnostic lung imaging, has prompted a review of reports of experiments on lung clearance with other aerosols. No direct comparison exists although it is clear that experimental inhalation insults which deliver to the alveoli a mass of material orders of magnitude greater than Technegas are well tolerated by human volunteers.
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页码:559 / 561
页数:3
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