ARE ROGUE CELLS AN INDICATOR OF CANCER RISK DUE TO THE ACTION OF BACTERIAL RESTRICTION ENDONUCLEASES

被引：17

作者：

AHUJA, YR

OBE, G

机构：

[1] UNIV ESSEN GESAMTHSCH, DEPT GENET, D-45117 ESSEN, GERMANY

[2] BHAGWAN MAHAVIR MED RES CTR, GENET UNIT, HYDERABAD 500004, ANDHRA PRADESH, INDIA

来源：

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS | 1994年 / 310卷 / 01期

关键词：

ROGUE CELLS; CANCER RISK; RESTRICTION ENDONUCLEASES; BACTERIAL INFECTIONS;

D O I：

10.1016/0027-5107(94)90013-2

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Cytogenetic surveys in normal individuals have occasionally shown the occurrence of cells with multiple chromosome-type aberrations in some of the subjects. These cells, which are rare, have been termed as rogue cells. Rogue cells, which have been observed worldwide, have a mysterious nature. It has been suggested that they may give rise to cancer. Various mechanisms have been considered for the causation of the rogue-cell phenomenon in the past but none of them appears to be fully justified. In this paper we propose their occurrence due to the action of bacterial restriction endonucleases.

引用

页码：103 / 112

页数：10

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