PULMONARY AND SYSTEMIC VASCULAR-RESPONSES TO 6-KETO-PGE1 IN THE CONSCIOUS LAMB

被引：24

作者：

LOCK, JE ^{[1
]}

OLLEY, PM ^{[1
]}

COCEANI, F ^{[1
]}

HAMILTON, F ^{[1
]}

DOUBILET, G ^{[1
]}

机构：

[1] HOSP SICK CHILDREN, DIV CARDIOL, TORONTO M5G 1X8, ONTARIO, CANADA

来源：

PROSTAGLANDINS & OTHER LIPID MEDIATORS | 1979年 / 18卷 / 02期

关键词：

D O I：

10.1016/0090-6980(79)90117-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

6-Keto-PGE1 is a potent direct dilator of the pulmonary and systemic circulations of the newborn lamb under both normoxic and hypoxic conditions. Its threshold dose is similar to that of PGI2 and PGE1. Under hypoxia, 6-keto-PGE1 appears equally effective on the pulmonary and systemic circulations, while under normoxia it predominantly affects the systemic circulation. © 1979.

引用

页码：303 / 309

页数：7

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