CONVERSION OF PHOSPHATIDYLETHANOLAMINE INTO PHOSPHATIDYLCHOLINE LABELED IN THE CHOLINE GROUP USING METHYL-IODIDE, 18-CROWN-6 AND POTASSIUM CARBONATE

被引：34

作者：

PATEL, KM

MORRISETT, JD

SPARROW, JT

机构：

[1] BAYLOR UNIV,COLL MED,DEPT MED,HOUSTON,TX 77030

[2] METHODIST HOSP,HOUSTON,TX 77030

来源：

LIPIDS | 1979年 / 14卷 / 06期

关键词：

D O I：

10.1007/BF02533539

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A chemical method for the conversion of phosphatidylethanolamine into phosphatidylcholine is described. Methyl iodide in the presence 18-crown-6 (1,4,7,10,13,16-hexaoxacyclooctadecane) and potassium carbonate in benzene is used to alkylate phosphatidylethanolamine in 2.5 hr at 37 C to give an isotopically enriched phosphatidylcholine. The product is purified conventionally and is obtained in 75% yield. © 1979 American Oil Chemists' Society.

引用

页码：596 / 597

页数：2

共 8 条

[1] SIMPLIFIED PREPARATION OF L-ALPHA-GLYCERYL PHOSPHORYL CHOLINE [J].