FLUTAMIDE IN THE TREATMENT OF HIRSUTISM

被引：21

作者：

MOTTA, T

MAGGI, G

PERRA, M

AZZOLARI, E

CASAZZA, S

DALBERTON, A

机构：

[1] Prima Clinica Ostetrico-Ginecologica, Università degli Studi, Milano

来源：

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS | 1991年 / 36卷 / 02期

关键词：

FLUTAMIDE; HIRSUTISM; ACNE; SEBORRHEA; HORMONES; HAIR GROWTH;

D O I：

10.1016/0020-7292(91)90772-W

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Ten hirsute women were treated with flutamide (250 mg/day) for 6 months to evaluate its effect. Hair growth as assessed by the Ferriman and Gallwey hair score was significantly reduced in all patients (P < 0.01). The only significant change in endocrine levels was an increase in serum androstenedione (P < 0.01). Acne and seborrhea improved markedly. No side effects were noted during the treatment. Our data suggest that the antiandrogenic properties of flutamide render it a suitable single agent in the treatment of hirsutism.

引用

页码：155 / 157

页数：3

共 9 条

[1]

CUSAN L, 1988, GYNECOL ENDOCRINO S2, V2, P256

[2] CLINICAL ASSESSMENT OF BODY HAIR GROWTH IN WOMEN [J].