CHROMOSOME CONDENSATION IN XENOPUS MITOTIC EXTRACTS WITHOUT HISTONE H1

被引：136

作者：

OHSUMI, K ^{[1
]}

KATAGIRI, C ^{[1
]}

KISHIMOTO, T ^{[1
]}

机构：

[1] HOKKAIDO UNIV,GRAD SCH SCI,DIV BIOL SCI,SAPPORO,HOKKAIDO 060,JAPAN

来源：

SCIENCE | 1993年 / 262卷 / 5142期

关键词：

D O I：

10.1126/science.8266099

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The contribution of histone H1 to mitotic chromosome condensation was examined with the use of a cell-free extract from Xenopus eggs, which transforms condensed sperm nuclei into metaphase chromosomes. When H1 was removed from the extract, the resultant metaphase chromosomes were indistinguishable from those formed in complete extract. Nucleosomal spacing was the same for both. Thus, H1 is not required for the structural reorganization that leads to condensed metaphase chromosomes in this egg extract.

引用

页码：2033 / 2035

页数：3

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