SEPARATION OF CELLULAR FROM EXTRACELLULAR CONTROLS OF DRINKING IN RATS BY FRONTAL BRAIN DAMAGE

被引:23
作者
BLASS, EM
机构
关键词
D O I
10.1126/science.162.3861.1501
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Rats that had undergone removal of the frontal portion of the brain, including the olfactory bulbs, did not drink, or drank less than controls, when subjected to cellular dehydration. These same animals drank normally in response to extracellular volume reduction. Rats from which only the olfactory bulbs had been removed drank normally in both tests. An essential part of the neurological system mediating drinking produced by cellular dehydration, but not by volume reduction, therefore lies within the frontal cortex or immediate subcortical tissue.
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页码:1501 / &
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