FUNCTIONALIZATION OF 2-METHYL-3-ORTHO-TOLYL-4(3H)-QUINAZOLINONE AND RELATED-COMPOUNDS THROUGH CARBANION REACTIONS AT THE 2-METHYL GROUP

被引：27

作者：

RATHMAN, TL ^{[1
]}

SLEEVI, MC ^{[1
]}

KRAFFT, ME ^{[1
]}

WOLFE, JF ^{[1
]}

机构：

[1] VIRGINIA POLYTECH INST & STATE UNIV, DEPT CHEM, BLACKSBURG, VA 24061 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1980年 / 45卷 / 11期

关键词：

D O I：

10.1021/jo01299a027

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

页码：2169 / 2176

页数：8

共 34 条

[1] SYNTHESIS AND CENTRAL NERVOUS-SYSTEM ACTIVITY OF QUINAZOLONES RELATED TO 2-METHYL-3-(ORTHO-TOLYL)-4(3H)-QUINAZOLONE (METHAQUALONE) [J].

AGER, IR ;

HARRISON, DR ;

KENNEWELL, PD ;

TAYLOR, JB .

JOURNAL OF MEDICINAL CHEMISTRY, 1977, 20 (03) :379-386

[2]

ALLA JA, 1974, J PHARM SCI, V63, P1627

[3]

BASS RG, 1975, TETRAHEDRON LETT, P2073

[4] Researches on quinazolines. XXXV. Stereoisomeric styryl derivatives of some 4-quinazolone alkyl iodides, and their bearing upon the problem of photosensitizing dyes [J].

Bogert, MT ;

Clark, H .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1924, 46 :1294-1301

[5] Researches on quinazolines (twenty-ninth paper). A further study of the stilbazoles, hydrazones and schiff bases of the 4-quinazolone group. [J].

Bogert, MT ;

Beal, GD .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1912, 34 :516-524

[6]

BOLTZE K H, 1963, Arzneimittelforschung, V13, P688

[7]

BROWN SS, 1973, CLIN PHARMACOL THER, V14, P314

[8] REACTION OF LITHIUM ALKYLS WITH ALDEHYDES AND KETONES - GENERAL STUDY [J].

BUHLER, JD .

JOURNAL OF ORGANIC CHEMISTRY, 1973, 38 (05) :904-906

[9] AROMATIC-SUBSTITUTION BY SRN1 MECHANISM [J].

BUNNETT, JF .

ACCOUNTS OF CHEMICAL RESEARCH, 1978, 11 (11) :413-420

[10] HINDERED INTERNAL-ROTATION ABOUT ARYL C-N BONDS IN ARYL SUBSTITUTED HETEROCYCLIC-COMPOUNDS - 3-ARYL-2-BENZYL-4(3H)-QUINAZOLINONES [J].

COLEBROOK, LD ;

GILES, HG .

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1975, 53 (22) :3431-3434

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