PLASMA GRANULOCYTE-COLONY-STIMULATING FACTOR CONCENTRATIONS ([G-CSF]) IN THE EARLY NEONATAL-PERIOD

被引:13
作者
RUSSELL, ARB [1 ]
DAVIES, EG [1 ]
MCGUIGAN, S [1 ]
SCOPES, GJD [1 ]
DALY, S [1 ]
GORDONSMITH, EC [1 ]
机构
[1] ST GEORGE HOSP,SCH MED,DEPT HAEMATOL,LONDON,ENGLAND
关键词
G-CSF; NEONATE; INFECTION; HYPERTENSION; LABOR;
D O I
10.1111/j.1365-2141.1994.tb04798.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We studied G-CSF concentrations ([G-CSF]) at birth and their relationship with neutrophil count, incidence of infection, gestational age, labour, and the presence of maternal pregnancy-induced hypertension. Plasma [G-CSF] were significantly elevated in babies with suspected infection and in those of hypertensive mothers, compared to healthy babies delivered by elective caesarian section (median [range] = 3101 [75 --> 5000] pg/ml and 153 [45-857] pg/ml versus 32 [11-266] pg/ml; P < 0.0001); and were unrelated to neutrophil count and gestational age. Initial high concentrations (> 100 pg/ml) declined by 7 d (P < 0.0001).
引用
收藏
页码:642 / 644
页数:3
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