PROLONGED PENTOBARBITAL NARCOSIS IN RATS WITH LESIONS OF MIDBRAIN RAPHE

被引：5

作者：

KOSTOWSKI, W

DOLFINI, E

机构：

[1] Istituto di Ricerche Farmacologiche, 20157 Milano, Mario Negri Via Eritrea

来源：

EUROPEAN JOURNAL OF PHARMACOLOGY | 1969年 / 6卷 / 01期

关键词：

Midbrain raphe lesion; Pentobarbital in brain; Pentobarbital narcosis; Sleep;

D O I：

10.1016/0014-2999(69)90068-5

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The midbrain raphe area is thought to be involved in sleep behaviour; stimulation of this area produces sedation and sleep whereas lesions of the same area elicit marked hypermotility. Pentobarbital increases sleeping time in midbrain lesioned rats and the percentage of animals sleeping. Concentrations of pentobarbital in brain are also reported. © 1969.

引用

页码：71 / +

页数：1

共 8 条

[1] BRODIE BB, 1953, J PHARMACOL EXP THER, V109, P26
[2] DAHLSTROM A, 1964, ACTA PHYSIOL SCAND, V62, P1
[3] GIACALONE E, IN PRESS
[4] HARVEY JA, 1964, J PHARMACOL EXP THER, V144, P24
[5] Konig JFR, 1963, RAT BRAIN STEREOTAXI
[6] STUDIES ON BEHAVIOURAL AND BIOCHEMICAL CHANGES IN RATS AFTER LESION OF MIDBRAIN RAPHE
KOSTOWSKI, W
GIACALONE, E
GARATTINI, S
VALZELLI, L
[J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 1968, 4 (04) : 371 - +
[7] KOSTOWSKI W, IN PRESS
[8] MOURET J, 1967, CR SOC BIOL, V161, P1600

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