UNCOUPLING OF THE PLATELET ALPHA-2-ADRENOCEPTOR ADENYLATE-CYCLASE SYSTEM BY N-ETHYLMALEIMIDE AND THE RESULTING EFFECT ON RECEPTOR DENSITY AND SENSITIVITY

被引：17

作者：

GARCIASEVILLA, JA ^{[1
]}

ARESO, P ^{[1
]}

GIRALT, MT ^{[1
]}

ULIBARRI, I ^{[1
]}

机构：

[1] UNIV BASQUE COUNTRY,FAC MED,DEPT PHARMACOL,LEIOA,SPAIN

来源：

EUROPEAN JOURNAL OF PHARMACOLOGY | 1988年 / 145卷 / 01期

关键词：

D O I：

10.1016/0014-2999(88)90354-8

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：91 / 95

页数：5

共 10 条

[1]

BERLAN M, 1986, BRIT J CLIN PHARMACO, V21, pP618

[2] EFFECTS OF ALPHA-2-ADRENOCEPTOR AGONISTS AND OF RELATED-COMPOUNDS ON AGGREGATION OF, AND ON ADENYLATE-CYCLASE ACTIVITY IN, HUMAN-PLATELETS [J].

CLARE, KA ;

SCRUTTON, MC ;

THOMPSON, NT .

BRITISH JOURNAL OF PHARMACOLOGY, 1984, 82 (02) :467-476

[3] CRITICAL-ASSESSMENT OF THE PLATELET ADENYLATE-CYCLASE SYSTEM AS A POTENTIAL MODEL FOR TESTING ALPHA-2 ADRENERGIC ACTIVITY [J].

FERRY, N ;

HENRY, D ;

BATTAIS, E ;

MARY, A ;

BONNE, C ;

HANOUNE, J .

BIOCHEMICAL PHARMACOLOGY, 1986, 35 (09) :1511-1516

[4] EFFECT OF PERTUSSIS TOXIN ON ALPHA-2-ADRENOCEPTORS - DECREASED FORMATION OF THE HIGH-AFFINITY STATE FOR AGONISTS [J].

GARCIASAINZ, JA ;

BOYER, JL ;

MICHEL, T ;

SAWYER, D ;

STILES, GL ;

DOHLMAN, H ;

LEFKOWITZ, RJ .

FEBS LETTERS, 1984, 172 (01) :95-98

[5] ALPHA-2-ADRENOCEPTOR-MEDIATED INHIBITION OF PLATELET ADENYLATE-CYCLASE ACTIVITY IN HEROIN-ADDICTS IN ABSTINENCE [J].

GARCIASEVILLA, JA ;

ULIBARRI, I ;

UGEDO, L ;

GUTIERREZ, M .

PSYCHOPHARMACOLOGY, 1987, 92 (03) :320-323

[6] PLATELET ALPHA-2-ADRENOCEPTORS IN HEROIN-ADDICTS DURING WITHDRAWAL AND AFTER TREATMENT WITH CLONIDINE [J].

GARCIASEVILLA, JA ;

UGEDO, L ;

ULIBARRI, I ;

GUTIERREZ, M .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1985, 114 (03) :365-374

[7]

GARCIASEVILLA JA, 1986, ARCH GEN PSYCHIAT, V43, P51

[8] CHANGES IN RABBIT PLATELET ALPHA-ADRENOCEPTOR AND BETA-ADRENOCEPTOR NUMBER AND PLATELET-AGGREGATION [J].

HAMILTON, CA ;

DEIGHTON, NM ;

JONES, CR ;

REID, JL .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1986, 130 (1-2) :145-149

[9]

JAKOBS KH, 1982, J BIOL CHEM, V257, P2829

[10] PLATELET ALPHA-ADRENERGIC BINDING AND BIOCHEMICAL RESPONSIVENESS IN DEPRESSED-PATIENTS AND CONTROLS [J].

SIEVER, LJ ;

KAFKA, MS ;

TARGUM, S ;

LAKE, CR .

PSYCHIATRY RESEARCH, 1984, 11 (04) :287-302

← 1 →