A 2ND CONSENSUS SEQUENCE OF ATP-REQUIRING PROTEINS RESIDES IN THE 21-KDA C-TERMINAL SEGMENT OF MYOSIN SUBFRAGMENT-1

被引：15

作者：

BURKE, M

RAJASEKHARAN, KN

MARUTA, S

IKEBE, M

机构：

[1] CASE WESTERN RESERVE UNIV,SCH MED,DEPT PHYSIOL & BIOPHYS,CLEVELAND,OH 44106

[2] CASE WESTERN RESERVE UNIV,DEPT BIOL,CLEVELAND,OH 44106

来源：

FEBS LETTERS | 1990年 / 262卷 / 02期

基金：

美国国家卫生研究院;

关键词：

ATP-binding domain; ATP-requiring enzyme; Myosin;

D O I：

10.1016/0014-5793(90)80185-L

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Previous comparisons of sequence homologies of ATP-requiring enzymes have defined three consensus sequences which appear to be involved in the binding of the nucleotide. One of these was identified in the N-terminal 27-kDa segment of the myosin heavy chain but the other two sequences have not hitherto been located in myosin. The present paper proposes that one of these other two consensus sequences is in the 21-kDa C-terminal portion of S1 and that it may contribute to the ATP binding domain. © 1990.

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页码：185 / 188

页数：4

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