TANDEM SEQUENCE REPEATS IN TRANSMEMBRANE CHANNEL PROTEINS

被引：101

作者：

WISTOW, GJ

PISANO, MM

CHEPELINSKY, AB

机构：

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1991年 / 16卷 / 05期

关键词：

D O I：

10.1016/0968-0004(91)90065-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The flow of ions and small molecules out of and between cells is mediated by various classes of transmembrane proteins. One group of putative channel proteins, including the abundant lens protein MlP, is widely distributed from prokaryotes to vertebrates. This article suggests that these proteins contain a structural twofold repeat and may have arisen by gene duplication. Such a model has implications for the tertiary structures of these important proteins.

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页码：170 / 171

页数：2

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