ASYMMETRIC CARBON-CARBON BOND FORMATION VIA SULFOXIDE-DIRECTED SN2' DISPLACEMENTS OF ACYCLIC ALLYLIC MESYLATES

被引：31

作者：

MARINO, JP ^{[1
]}

VISO, A ^{[1
]}

DELAPRADILLA, RF ^{[1
]}

FERNANDEZ, P ^{[1
]}

机构：

[1] CSIC, INST QUIM ORGAN, E-28006 MADRID, SPAIN

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1991年 / 56卷 / 04期

关键词：

D O I：

10.1021/jo00004a002

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The addition of organocyanocuprates to acylic allylic mesylates bearing a chiral sulfoxide in the 2-position occurs with complete S(N)2' regioselectivity, high E/Z stereoselectivity (15:1) and high asymmetric induction to produce enantiometrically pure trisubstituted vinyl sulfoxides.

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收藏

页码：1349 / 1351

页数：3

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