ANCYLOSTOMA-CANINUM - GLUTATHIONE STIMULATES FEEDING IN 3RD-STAGE LARVAE BY A SULFHYDRYL-INDEPENDENT MECHANISM

被引：13

作者：

HAWDON, JM ^{[1
]}

SCHAD, GA ^{[1
]}

机构：

[1] UNIV PENN,DEPT PATHOBIOL,PHILADELPHIA,PA 19104

来源：

EXPERIMENTAL PARASITOLOGY | 1993年 / 77卷 / 04期

关键词：

D O I：

10.1006/expr.1993.1110

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

The reduced form of the tripeptide glutathione has been reported to reinitiate feeding by third-stage larvae of the hookworm Ancylostoma caninum. Investigations were conducted with the GSH analogue ophthalmic acid to determine the mechanism by which GSH stimulates feeding. Ophthalmic acid stimulated feeding, beginning at 1-2.5 mM and reaching a maximum by 10-15 mM, and also enhanced serum-stimulated feeding. The results indicate that GSH stimulates feeding by a specific, sulfhydryl-independent mechanism. © 1993 Academic Press. All rights reserved.

引用

页码：489 / 491

页数：3

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