PHOSPHORYLATION AND DEPHOSPHORYLATION OF PROTEIN IN REGULATING CELLULAR FUNCTION

被引：30

作者：

KUROSAWA, M

机构：

[1] First Department of Internal Medicine, Gunma University of Medicine, Maebashi, Shyowa-machi

来源：

JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS | 1994年 / 31卷 / 03期

关键词：

PROTEIN KINASE; PROTEIN PHOSPHATASE;

D O I：

10.1016/1056-8719(94)90075-2

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Phosphorylation state of cellular proteins reflects the balance between the activities of protein kinases and phosphoprotein phosphatases. The increase in cellular protein phosphorylation in response to stimuli can be achieved by either activating protein kinases and/or promoting the turnover of the protein phosphatases. This review will summarize current knowledge of the control of phosphorylation and dephosphorylation of protein in cells.

引用

页码：135 / 139

页数：5

共 33 条

[1] INSULIN AND INSULIN-LIKE GROWTH-FACTOR RECEPTORS IN THE NERVOUS-SYSTEM
ADAMO, M
RAIZADA, MK
LEROITH, D
[J]. MOLECULAR NEUROBIOLOGY, 1989, 3 (1-2) : 71 - 100
[2] REGULATION AND KINETICS OF THE ACTIN-MYOSIN-ATP INTERACTION
ADELSTEIN, RS
EISENBERG, E
[J]. ANNUAL REVIEW OF BIOCHEMISTRY, 1980, 49 : 921 - 956
[3] THE CD4 AND CD8 ANTIGENS ARE COUPLED TO A PROTEIN-TYROSINE KINASE (P56LCK) THAT PHOSPHORYLATES THE CD3 COMPLEX
BARBER, EK
DASGUPTA, JD
SCHLOSSMAN, SF
TREVILLYAN, JM
RUDD, CE
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (09) : 3277 - 3281
[4] BISHOP JM, 1982, ANNU REV BIOCHEM, V52, P302
[5] CASTAGNA M, 1982, J BIOL CHEM, V257, P7847
[6] THE STRUCTURE AND REGULATION OF PROTEIN PHOSPHATASES
COHEN, P
[J]. ANNUAL REVIEW OF BIOCHEMISTRY, 1989, 58 : 453 - 508
[7] MULTIPLE, DISTINCT FORMS OF BOVINE AND HUMAN PROTEIN-KINASE-C SUGGEST DIVERSITY IN CELLULAR SIGNALING PATHWAYS
COUSSENS, L
PARKER, PJ
RHEE, L
YANGFENG, TL
CHEN, E
WATERFIELD, MD
FRANCKE, U
ULLRICH, A
[J]. SCIENCE, 1986, 233 (4766) : 859 - 866
[8] TRANSFORMATION BY ONCOGENES ENCODING PROTEIN-KINASES INDUCES THE METASTATIC PHENOTYPE
EGAN, SE
WRIGHT, JA
JAROLIM, L
YANAGIHARA, K
BASSIN, RH
GREENBERG, AH
[J]. SCIENCE, 1987, 238 (4824) : 202 - 205
[9] THE PROTEIN-KINASE FAMILY - CONSERVED FEATURES AND DEDUCED PHYLOGENY OF THE CATALYTIC DOMAINS
HANKS, SK
QUINN, AM
HUNTER, T
[J]. SCIENCE, 1988, 241 (4861) : 42 - 52
[10] HATHAWAY GM, 1982, CURR TOP CELL REGUL, V21, P101

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