SELECTIVE N-METHYLATION OF ETHYL-ESTERS OF 3-(1H-IMIDAZOL-4-YL)-2-PROPENOIC ACID

被引：14

作者：

MAWLAWI, H

MONJE, MC

LATTES, A

RIVIERE, M

机构：

[1] Laboratoire Des Imrcp, URA au CNRS 470, Université Paul Sabatier, Toulouse, 31062

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1992年 / 29卷 / 06期

关键词：

D O I：

10.1002/jhet.5570290643

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Methods of selective methylation of the nitrogen atoms of the ethyl ester of 3-(1H-imidazol-4-yl)-2-propenoic acid are reported. The nitrogen atom alpha to the ethylenic chain was methylated after protection of the beta nitrogen with a phenacyl group.

引用

页码：1621 / 1624

页数：4

共 11 条

[1]

Anglin Jr J.H., 1976, COSMET TOILETRIES, V91, P47

[2]

COLIN CD, 1981, AUST J CHEM, V34, P1739

[3] SARCODICTYIN-A AND SARCODICTYIN-B, NOVEL DITERPENOIDIC ALCOHOLS ESTERIFIED BY (E)-N(1)-METHYLUROCANIC ACID - ISOLATION FROM THE MEDITERRANEAN STOLONIFER SARCODICTYON-ROSEUM [J].