HORMONAL-CONTROL OF GLYCOGEN-METABOLISM - PHOSPHORYLATION OF PROTEIN PHOSPHATASE INHIBITOR-1 INVIVO IN RESPONSE TO ADRENALINE

被引:128
作者
FOULKES, JG
COHEN, P
机构
[1] Department of Biochemistry, Medical Sciences Institute, University of Dundee, Dundee
来源
EUROPEAN JOURNAL OF BIOCHEMISTRY | 1979年 / 97卷 / 01期
关键词
D O I
10.1111/j.1432-1033.1979.tb13109.x
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Inhibitor‐1 has been shown to be phosphorylated in skeletal muscle in vivo. In normal fed animals the degree of phosphorylation was 31 ± 7% and this value increases to 70 ± 12% following an intravenous injection of adrenaline. The results imply that the phosphorylation of inhibitor‐1 may be equally as important as the phosphorylation of phosphorylase kinase in elevating the levels of phosphorylase a. The role of inhibitor‐1 in metabolism is discussed. Copyright © 1979, Wiley Blackwell. All rights reserved
引用
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页码:251 / 256
页数:6
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