IMMUNOLOGICAL-TOLERANCE TO MANY SELF EPITOPES MAY BE UNNECESSARY

被引：9

作者：

PREHN, RT ^{[1
]}

机构：

[1] UNIV WASHINGTON,DEPT PATHOL,SEATTLE,WA 98195

来源：

SCANDINAVIAN JOURNAL OF IMMUNOLOGY | 1990年 / 32卷 / 03期

关键词：

D O I：

10.1111/j.1365-3083.1990.tb02923.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The demonstration of the existence of antigenic mimicry suggests that immunological tolerance to self antigens may be an insufficient basis for distinguishing self from non‐self. However, some data suggest that even in the absence of tolerance most self epitopes would not immunize the host and that tolerance to all self epitopes may, therefore, not be necessary for the prevention of autoimmune disease. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：293 / 296

页数：4

共 12 条

[1] ROLE OF AFFERENT LYMPHATICS IN REJECTION OF SKIN HOMOGRAFTS [J].