EPIDURAL LIPOMATOSIS IN STEROID-TREATED PATIENTS

被引:74
作者
FESSLER, RG
JOHNSON, DL
BROWN, FD
ERICKSON, RK
REID, SA
KRANZLER, L
机构
[1] Department of Neurological Surgery, University of Florida, College of Medicine, Gainesville, FL
[2] Section of Neurosurgery, University of Chicago Medical Center, Chicago, IL
关键词
BACK PAIN; EPIDURAL LIPOMATOSIS; RADICULOPATHY; SPINAL CORD COMPRESSION; SPINAL STENOSIS; STEROID THERAPY;
D O I
10.1097/00007632-199202000-00011
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Epidural lipomatosis is a condition in which excess adipose tissue is deposited circumferentially about the spinal cord in the epidural space. It is most frequently seen in patients on chronic steroid treatment for a variety of medical problems and can present as nonspecific back pain, radiculopathy, or frank spinal cord compression. Diagnosis and treatment have generally relied on multilevel decompressive laminectomy after myelography and computed tomography. The immunocompromised state and the reported postoperative mortality (22%) of these patients, however, suggests that nonoperative therapy may be preferable whenever possible. Five cases of epidural lipomatosis are reported, and previous literature is reviewed for presentation, evaluation, and treatment of this condition.
引用
收藏
页码:183 / 188
页数:6
相关论文
共 15 条
[1]  
Archer C.R., Smith K.R., Extradural lipomatosis simulating an acute herniated nuclcus pulposus, J Neurosurg, 57, pp. 559-562, (1982)
[2]  
Badami J., Hinck V., Symptomatic deposition of epidural fat in a morbidly obese woman, AJNR, 3, pp. 664-665, (1982)
[3]  
Butcher D.L., Sahn S.A., Epidural lipomatosis: A complication of corticosteroid therapy, Ann Intern Med, 90, (1979)
[4]  
Chapman P.H., Martuza R.L., Poletti C.E., Darchmer A.W., Symptomatic spinal epidural lipomatosis associated with Cushing’s syndrome, Neurosurgery, 8, pp. 724-727, (1981)
[5]  
George W.E., Wilmot M., Greenhouse A., Hammeke M., Medical management of steroid-induced epidural lipomatosis, N Engi J Med, 308, pp. 316-319, (1983)
[6]  
Godeau P., Brunet P., Wechsler B., Fohanno D., Lipomatose extra-durale compressive, accident inhabituel de Ia corticotherapie, Nouv Presse Med, 8, pp. 3889-3891, (1979)
[7]  
Guegan Y., Fardoun R., Launois B., Pecker J., Spinal cord compression by extradural fat after prolonged corticosteroid therapy: Case report, J Neurosurg, 56, pp. 267-269, (1982)
[8]  
Haid R.W., Kaufman H.H., Schocet S.S., Marano G.D., Epidural lipomatosis simulating an epidural abscess: Case report and literature review, Neurosur-Gery, 21, pp. 744-747, (1987)
[9]  
Lee M., Lekias J., Gubbay S.S., Hurst P.E., Spinal cord compression by extradural fat after renal transplantation, Medj Aust, 1, pp. 201-203, (1975)
[10]  
Lipson S.J., Naheedy M.H., Kaplan M.M., Bienfano D.C., Spinalstenosiscaused by epidural lipomatosis in Cushing’s syndrome, N Engl J Med, 302, (1980)