SN2-LIKE TRANSITION-STATE FOR METHYL TRANSFER CATALYZED BY CATECHOL-O-METHYLTRANSFERASE

被引：31

作者：

HEGAZI, MF

BORCHARDT, RT

SCHOWEN, RL

机构：

[1] UNIV KANSAS,DEPT BIOCHEM,MCCOLLUM LABS,LAWRENCE,KS 66045

[2] UNIV KANSAS,DEPT CHEM,LAWRENCE,KS 66045

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1976年 / 98卷 / 10期

关键词：

D O I：

10.1021/ja00426a079

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：3048 / 3049

页数：2

共 13 条

[1] PURIFICATION OF CATECHOL-O-METHYLTRANSFERASE BY AFFINITY CHROMATOGRAPHY [J].

BORCHARDT, RT ;

CHENG, CF ;

THAKKER, DR .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1975, 63 (01) :69-77

[2] CATECHOL O-METHYLTRANSFERASE .1. KINETICS OF TROPOLONE INHIBITION [J].

BORCHARDT, RT .

JOURNAL OF MEDICINAL CHEMISTRY, 1973, 16 (04) :377-382

[3] MODEL CALCULATIONS OF KINETIC ISOTOPE-EFFECTS IN NUCLEOPHILIC-SUBSTITUTION REACTIONS [J].

BRON, J .

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1974, 52 (06) :903-909

[4]

COWARD JK, 1972, BIOCHEM PHARMACOL, V21, P1200, DOI 10.1016/0006-2952(72)90114-1

[5] KINETIC STUDIES ON CATECHOL O-METHYLTRANSFERASE - PRODUCT INHIBITION AND NATURE OF CATECHOL BINDING-SITE [J].

COWARD, JK ;

SLISZ, EP ;

WU, FYH .

BIOCHEMISTRY, 1973, 12 (12) :2291-2297

[6] CATECHOL-O-METHYLTRANSFERASE [J].

FLOHE, L .

INTERNATIONAL PHARMACOPSYCHIATRY, 1974, 9 (01) :52-60

[7]

FLOHE L, 1970, Biochimica et Biophysica Acta, V220, P469, DOI 10.1016/0005-2744(70)90278-0

[8]

MELVILLE DB, 1947, J BIOL CHEM, V169, P419

[9]

NIKODEJEVIC B, 1970, J PHARMACOL EXP THER, V174, P83

[10]

SCHLENK F, 1968, P INT C METHODS PREP

← 1 2 →