ENERGY-LINKED ALTERATION OF MITOCHONDRIAL PERMEABILITY TO ANIONS

被引：26

作者：

BRIERLEY, GP

机构：

[1] Department of Physiological Chemistry, College of Medicine Ohio State University, Columbus

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1969年 / 35卷 / 03期

关键词：

D O I：

10.1016/0006-291X(69)90512-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Evidence is presented which indicates that a massive uptake of KCl and osmotic swelling which occurs when respiring mitochondria are treated with valinomycin is the result of a transient alkalization of the membrane. Energy-linked contraction and KCl extrusion follow the initial swelling phase spontaneously. The data appear to be consistent with the predictions of Mitchell's chemiosmotic coupling hypothesis. © 1969.

引用

页码：396 / &

共 11 条

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[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1968, 162 (04) : 487 - +

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