APORPHINES .25. TRIMETHYLSILYL DERIVATIVES OF N-METHYL AND N-PROPYL APORPHINES - GAS-CHROMATOGRAPHIC AND MASS-SPECTROMETRIC PROPERTIES

被引:7
作者
GREEN, JF [1 ]
EVANS, JV [1 ]
NEUMEYER, JL [1 ]
VOUROS, P [1 ]
机构
[1] NORTHEASTERN UNIV,DEPT MED CHEM & PHARMACOL,BOSTON,MA 02115
来源
BIOMEDICAL MASS SPECTROMETRY | 1979年 / 6卷 / 07期
关键词
D O I
10.1002/bms.1200060704
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
A series of synthetic, semisynthetic and naturally occurring aporphine alkaloids were converted to the O‐trimethylsilyl derivatives, and analyzed by gas chromatography mass spectrometry. A discussion of discussion of structurally informative fragment ions along with gas chromatographic data is presented. Their applicability to the analysis of biological metabolites of apomorphine, a CNS active structural analog of dopamine, is discussed. Copyright © 1979 Heyden & Son Ltd
引用
收藏
页码:282 / 286
页数:5
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