DECREASED PROPERDIN ACTIVITY IN ACUTE GLOMERULONEPHRITIS

被引：42

作者：

GEWURZ, H

PICKERING, RJ

NAFF, G

SNYDERMAN, R

MERGENHAGEN, SE

GOOD, RA

机构：

[1] Departments of Pediatrics, Surgery, and Microbiology, University of Minnesota School of Medicine, Minneapolis, MN

[2] Department of Medicine, Case-Western Reserve University School of Medicine, Immunology Section of the National Institute of Dental Research, Cleveland, OH

[3] Department of Medicine, Case-Western Reserve University School of Medicine, Cleveland, OH

[4] Immunology Section, National Institute of Dental Research, Bethesda, MD

来源：

INTERNATIONAL ARCHIVES OF ALLERGY AND APPLIED IMMUNOLOGY | 1969年 / 36卷 / 06期

关键词：

D O I：

10.1159/000230780

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Properdin regularly was undetectable in the serum of patients with acute glomerulonephritis. It was reduced in about 50% of patients with hypocomplemcntcmic chronic glomerulonephritis, but was in the normal range in patients with normocomplementemic glomerulonephritis. The depletion of properdin in acute glomerulonephritis suggests that this protein might be involved in the consumption of classical C′3 so characteristic of this disease. © 1969 S. Karger AG, Basel.

引用

页码：592 / +

页数：1

共 18 条

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