QUANTITATIVE-DETERMINATION OF LYMPHOCYTE ACTH1-39

被引：7

作者：

FERREIRA, JA

CARSTENS, ME

TALJAARD, JJF

机构：

[1] MRC Research Unit for the Neurochemistry of Mental Diseases, Department of Chemical Pathology, University of Stellenbosch, Tygerberg, 7505

来源：

NEUROPEPTIDES | 1990年 / 15卷 / 01期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/0143-4179(90)90154-Q

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A method was developed for quantitative measurement of ACTH1-39, produced by human lymphocytes. It was shown that pH adjustment to 2 was essential for processing of the precursor molecule proopiomelanocortin (POMC). Linearity between time of incubation and ACTH production was shown. The existence of specific endopeptidases in lymphocytes for processing of the POMC molecule remains doubtful. © 1990.

引用

页码：11 / 15

页数：5

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