SELECTIVE BINDING OF THE SCORPION-VENOM INSECT TOXIN TO INSECT NERVOUS-TISSUE

被引：32

作者：

TEITELBAUM, Z ^{[1
]}

LAZAROVICI, P ^{[1
]}

ZLOTKIN, E ^{[1
]}

机构：

[1] HEBREW UNIV JERUSALEM, DEPT ZOOL, JERUSALEM 91000, ISRAEL

来源：

INSECT BIOCHEMISTRY | 1979年 / 9卷 / 04期

关键词：

insect toxin; Locusta; nervous tissue; radio-iodination; scorpion venom; selective action; specific binding;

D O I：

10.1016/0020-1790(79)90080-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Insect toxin (IT), a highly lethal and paralytic protein purified from scorpion venom, has been used in binding experiments with different tissue preparations of Locusta migratoria. A clear, specific binding of a high affinity was obtained only between the radio-iodinated toxin and the nervous tissue extracts. Assays with a similar nervous tissue preparation derived from a crustacean (crayfish) resulted in a low and non-specific binding of the toxin. The present data support the notion of a selective action of IT on insect nervous tissue and may indicate a certain structural uniqueness in this system. © 1979.

引用

页码：343 / 346

页数：4

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